Advance in assay method of endotoxin and related pyrogen
نویسندگان
چکیده
منابع مشابه
An Assay Method for Leukocyte Pyrogen
A method for assaying leukocyte pyrogen is described which is shown to remain valid despite the presence of very large amounts of bacterial endotoxin. It uses a combination of two procedures to inactivate endotoxin: incubation in normal rabbit plasma for 24 hr at 37 degrees C, and injection into rabbits rendered refractory to endotoxin. The validity of the assay was confirmed by formal statisti...
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15 صفحه اولHuman monocytoid cell lines as indicators of endotoxin: comparison with rabbit pyrogen and Limulus amoebocyte lysate assay.
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متن کاملNewly Developed Endotoxin Measurement Method (the Endotoxin Activity Assay) May Reflect the Severity of Sepsis
Objectives: Endotoxin (ET) is a structural molecule of the Gram-negative bacilli extracellular membrance, which activates targeted cells including macrophages and neutrophils, and causes septic shock. But it is known that the conventional ET measurement method has many problems; for example, a discrepancy between plasma ET concentration and clinical manifestration in the septic patients has bee...
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ژورنال
عنوان ژورنال: Nihon Toseki Igakkai Zasshi
سال: 1998
ISSN: 1883-082X,1340-3451
DOI: 10.4009/jsdt.31.1163